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帕利哌酮与利培酮治疗精神分裂症和分裂样精神病的疗效及社会功能差异分析 被引量:3

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摘要 目的探讨精神分裂症及分裂样精神病患者分别接受帕利哌酮及利培酮治疗的疗效及社会功能改善情况。方法将2015-07—2016-09入院就诊的精神分裂症及分裂样精神病患者96例予以随机分组,分别给予利培酮治疗(A组)和帕利哌酮治疗(B组),每组48例,对比组间疗效。结果治疗前两组患者的PANSS及PSP评分对比均差异无统计学意义(P>0.05);治疗后两组的PANSS评分对比差异无统计学意义(P>0.05),B组的PSP评分相对更高(P<0.05);B组的TESS评分为较A组下降明显(P<0.05)。B组的不良反应发生率2.08%显著低于A组的14.58%,差异有统计学意义(P<0.05)。结论帕利哌酮及利培酮对于精神分裂症及分裂样精神病均有一定疗效,但帕利哌酮有更优疗效,且对于患者社会功能改善效果确切。
作者 杨妍
出处 《中国疗养医学》 2017年第8期882-883,共2页 Chinese Journal of Convalescent Medicine
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