复方甘草酸苷胶囊和消银颗粒治疗玫瑰糠疹的药物经济学分析

Pharmacoeconomic analysis of Compound Glycyrrhizin Capsules and Xiaoyin granules in treatment of pityriasis rosea

目的通过对复方甘草酸苷胶囊和消银颗粒治疗玫瑰糠疹的药物经济学情况进行分析,为临床选择最佳用药方案提供参考。方法选取2015年3月至2016年9月于广东省中山市坦洲医院门诊治疗的186例玫瑰糠疹患者为研究对象,随机分为A、B两组,各93例。A组患者口服复方甘草酸苷胶囊,B组患者给予消银颗粒,比较两组患者疗效和不良反应发生情况,并进行成本-效果分析。结果 A组、B组患者总有效率分别为79.57%、83.87%,差异无统计学意义(P>0.05),成本-效果比分别为1.67、1.09,差异有统计学意义(P<0.05)。结论复方甘草酸苷胶囊和消银颗粒治疗玫瑰糠疹的疗效和安全性相当,但消银颗粒能减少患者的经济负担,节省卫生资源,具有更好的经济性。

Objective The pharmacoeconomics of Compound Glycyrrhizin Capsules and Xiaoyin granules in treatment of pityriasis rosea analysis,provide a reference for clinical selection of the best regimen.Methods 186 cases of pityriasis rosea were selected from March 2015 to September 2016 in Guangdong province Zhongshan city Tanzhou hospital outpatient treatment as the research object,randomly divided into A,B two groups,93 cases in each.Patients in group A were treated with oral administration of Compound Glycyrrhizin Capsules,and patients in group B were treated with the elimination of silver particles.The efficacy and adverse reactions were compared between the two groups.Results The total effective rate of A group and B group were 79.57% and 83.87%, respectively.The difference was not statistically significant（P〉0.05）,and the cost-effectiveness ratio was about 1.67 and 1.09,respectively.The difference was statistically significant（P〈0.05）.Conclusion The efficacy and safety of Compound Glycyrrhizin Capsules and Xiaoyin granules in treatment of pityriasis rosea,but Xiaoyin granules can reduce the economic burden of patients,saving medical resources, better economy.