肿瘤患者PICC导管相关性血栓形成的相关因素分析

Risk factors of peripherally inserted central catheter-related thrombosis in cancer patients

目的探讨肿瘤患者PICC导管相关性血栓形成的相关因素。方法对1 030例PICC带管肿瘤患者进行上肢静脉超声检查并分析临床资料。结果 PICC带管肿瘤患者PICC导管相关性血栓发生率为5.44%;其中无症状血栓占76.79%,有症状血栓占23.21%。肠外营养的使用、导管相关并发症、高血压、带管时间、年龄>60岁5个因素对血栓的发生有显著影响(P<0.05,P<0.01)。结论 PICC导管相关性血栓临床表现多数无症状,PICC导管相关性血栓形成的风险因素较多,需针对风险因素进行预警管理干预,以降低其发生率。

Objective To explore risk factors of peripherally inserted central catheter （PICC）-related thrombosis in cancer patients. Methods Upper extremities of 1 030 cancer patients who underwent PICC placement were examined by Doppler ultrasound and clinical data of these patients were collected. Results The incidence rate of PICC-related thrombosis in cancer patients was 5.44%, with asymptomatic thrombosis accounting for 76.79% and symptomatic events accounting for 23. 21%. Parenteral nutrition administration, PICC-related complications, hypertension, duration of PICC placement, age greater than 60 years were associated with PICC-related thrombosis （P〈0.05, P〈0. 01）. Conclusion Asymptomatic PICC-related thrombosis is more common and PICC-related thrombosis is caused by several factors. It is necessary to take targeted measures to reduce the incidence.