韦太夫雷登沙门菌引起的食物中毒分析

Analysis of food poisoning caused by Salmonella weltevreden

目的探讨韦太夫雷登沙门菌引起食物中毒后患者的临床表现及患者某些检测指标变化和后果。方法对2016年5月25日成都市某高校发生的一起食物中毒患者的大便标本进行致病菌的培养分离鉴定,并对患者的血常规、出凝血时间、C反应蛋白(CRP)及D-二聚体(D-D)进行监测。结果 69例患者均由被韦太夫雷登沙门菌污染的食物引起中毒,69例中毒者的大便标本均检测到了韦太夫雷登沙门菌,患者的临床表现均有高热、腹痛、腹泻,同时伴有水样便;91.3%的患者血常规出现不同程度的WBC升高,20.3%的患者大便出现白细胞(WBC)增多,所有患者的CRP均出现异常增高,部分患者的PCT、D-D及凝血功能出现异常。结论韦太夫雷登沙门菌导致的食物中毒病情严重,部分患者生理功能出现严重改变,危及生命,在加强食品卫生的同时,应特别注意该种细菌带给人类生命的危害。

Objective To explore the clinical manifestation,physiological index changes and consequences of food poisoning caused by Salmonella weltevreden（S.weltevreden）.Methods Bacteria culture and isolation were proceeded with stool specimens from patients who got food poisoning in a university in Chengdu on May 25,2016.Blood routine examination,coagulation function test,C-reactive protein（CRP）and D-Dimer tests were also proceeded with whole blood or plasma samples from food poisoning patients.Results A total of 69 patients were identified food poisoning caused by S.weltevreden,and S.weltevreden was isolated from all of their stools specimens.The common clinical manifestation of these patients were high fever,stomachache and diarrhea with watery stool.91.3% of patients had a blood routine white blood cells（WBC）increasing in different degrees,20.3% of patients had a WBC increasing in stool specimens.The CRP level of all patients were abnormally increased,and the procalcitonin（PCT）level,DDimer level and coagulation function were also abnormal.Conclusion The clinical symptoms of food poisoning caused by S.weltevreden are seriously,even physiological function of some patients are changed tremendously or life-threateningly.We should pay attention to the dangers of S.weltevreden to human life in addition to strengthen food safety.