泰丸合青蒿鳖甲汤加味治疗更年期综合征80例分析

Analysis of 80 cases of climacteric syndrome treated by Tai pill and Qinghao Biejia Decoction

目的 研究分析泰丸合青蒿鳖甲汤加味治疗更年期综合症的临床效果。方法 选取宁波市奉化区中医医院2015年2月-2016年10月收治的80例更年期综合征患者为研究对象,随机分为对照组和实验组,每组40例。对照组患者给予常规治疗,包括维生素以及1 mg戊酸雌二醇,1次/d。实验组患者进行泰丸合青蒿鳖甲汤加味治疗,1天分2次服用,清水浸泡30 min,2组治疗时间均为40 d。比较分析2组患者治疗效果。结果 经过对应的治疗后,实验组患者的治疗有效率（95.0%）显著高于对照组（75.0%）,差异具有统计学意义（P〈0.05）。治疗后,实验组与对照组均未出现严重的不良反应,安全性较好。2组患者在治疗前后进行肝肾结果检测以及便、血、尿检测结果未见异常以及相关的毒副反应。实验组患者烦躁易怒以及五心烦热体征消失率分别为75.0%、80.0%,对照组患者消失率为50.0%、60.0%。结论 泰丸合青蒿鳖甲汤加味治疗更年期综合症临床效果较好,安全性较好,具有临床进一步推广和应用的意义。

Objective To study the clinical effect analysis of Thailand pill and Qinghao Biejia Decoction in treating climacteric syndrome. Methods 80 cases of climacteric syndrome treated in our hospital from February 2015 to October 2016 were selected and randomly divided into the control group and the experimental group, with 40 patients in each group. Patients in the control group were given conventional treatment, including vitamins and 1 mg estradiol valerate, 1 times per day. Patients in the experimental group were given Thailand pill and Qinghao Biejia decoction, two times a day to take water for 30min, the two groups were treated for 40 days. The therapeutic effects of the patients in the experimental group and the control group were compared and analyzed. Results After the corresponding treatment, the effective rate of treatment in the experimental group （95.0 %） was significantly higher than that in the control group （75.0 %）, the difference was statistically significant （P〈0.05）. After treatment, there were no serious adverse reactions in the experimental group and the control group, and the safety was better. Two groups of patients before and after treatment of liver and kidney test, as well as feces, blood and urine test results are not unusual, and related adverse reactions. The irritable and Fanre signs disappeared rate in the experimental group were 75.0 % and 80.0 %,the disappearance rate in the control group were 50.0 % and 60.0 %. Conclusion The clinical effect of Thailand pill and Qinghao Biejia.0 Decoction in treating climacteric syndrome, good safety, with further clinical promotion and application significance.