对ICU重型颅脑外伤患者实施右美托咪定联合营养干预对其认知功能恢复效果及预后的影响

Effect of dexmedetomidine combined with nutritional intervention in the cognitive function recovery and prognosis of patients in ICU severe cranial traumatic brain injury

目的 探究右美托咪定联合营养干预对ICU重型颅脑外伤患者认知功能恢复效果及预后的影响。方法 选取2016年2月20日-2016年12月30日浙江省宁波市鄞州人民医院ICU重型颅脑外伤患者100例,随机分为2组,对照组联合营养干预,实验组联合右美托咪定与营养干预。结果 2组干预后的PACHEⅡ评分、GCS评分以及机械通气时间、住院时间相比,差异有统计学意义（P〈0.05）;实验组认知功能恢复程度优于对照组（P〈0.05）。结论 ICU重型颅脑外伤患者接受右美托咪定与营养干预的价值较高。

Objective To explore the effect of dexmedetomidine combined with nutritional intervention on cognitive function recovery and prognosis of patients with severe cranial traumatic brain injury in ICU. Methods A total of 100 patients with severe cranial traumatic brain injury from February 20, 2016 to December 30, 2016 in our hospital ICU were selected and randomly divided into two groups, the control group were given nutrition intervention, the experimental group combined with dexmedetomidine and nutritional intervention. Results The difference of PACHE Ⅱscore, GCS score, mechanical ventilation time, and hospitalization timebetween the 2 groups was statistically significant （P〈0.05）; The recovery of cognitive function in the experimental group was better than that in the control group （P〈0.05）. Conclusion The value of dexmedetomidine and nutritional intervention in patients with severe cranial traumatic brain injury in ICU is higher.