心理干预联合乌司他丁、血必净治疗重症脓毒血症的临床疗效观察

The psychological intervention of ustradine in the treatment of severe sepsis

目的 探讨心理干预联合乌司他丁、血必净治疗重症脓毒血症的临床疗效观察。方法 选取2016年1月-2017年3月于本院诊治的重症脓毒血症患者76例,依不同护理干预模式分为对照组与观察组,各38例。对照组用乌司他丁＋血必净治疗,观察组用乌司他丁＋血必净＋心理干预治疗;对2组患者治疗前后临床症状改善情况、心理状态（SAS、SDS评分）改善情况,并将所获相关数据作做对比分析。结果 乌司他丁＋血必净＋心理干预（观察组）治疗重症脓毒血症患者临床效果优于乌司他丁＋血必净（对照组）临床治疗效果,患者炎症因子水平改善情况优于对照组、SAS及SDS评分改善情况优于对照组,差异有统计学意义（P〈0.05）。结论 重症脓毒血症患者选择乌司他丁＋血必净＋心理干预治疗效果显著,可有效降低患者体内炎症因子水平,并充分改善患者心理状态,值得临床上广泛应用。

Objective To explore the psychological intervention effect of ulinastatin combined with Xuebijing in the treatment of severe sepsis. Methods 76 patients with severe sepsis in our hospital from January 2016 to March 2017 were selected,and according to the different nursing intervention divided into observation group and control group,38 cases in each groups. control group with Ulinastatin and Xuebijing treatment, observation group with Ulinastatin and Xuebijing plus psychological intervention; before and after treatment in two groups of patients with clinical symptoms, psychological status （SAS and SDS score） to improve the situation, and the related data for comparative analysis. Results Ulinastatin and Xuebijing＋psychological intervention （observation group） the clinical effect of treatment of severe sepsis patients than Ulinastatin and Xuebijing （control group） the clinical treatment effect of inflammatory factors in patients with improvement than the control group, SAS and SDS was better than that of control group, the difference was statistically significant （P〈0.05）. Conclusion severe sepsis patients choose the Ulinastatin＋Xuebijing＋psychological intervention of ulinastatin Xuebijing significantly, can effectively reduce the level of inflammatory factors in the patients, and fully improve the psychological status of patients, is worthy of clinical application.