肠道微生物对消化系统疾病的影响

Effects of intestinal microbes on digestive system diseases

人类肠道内存在数以亿计的微生物,他们及其代谢产物共同维持着人类肠道内稳态,参与机体代谢及免疫保护功能。目前研究的大多数消化系统疾病都与肠道微生物的异常紧密相关,并且随着益生菌制剂以及粪菌移植技术在消化系统疾病治疗方面的备受青睐,肠道微生物已经成为了现代研究的一个热点和难点。文章就与肠道微生物相关的消化系统疾病进行综述,并且简要介绍粪菌移植及部分中药在调节肠道微生态方面的功效。

There are hundreds of millions of microbes in human intestinal tract, they and their metabolic products, which are involved in the body＇s metabolism and immune protection function, contribute to the human gut homeostasis. Most of the present studies of the digestive system diseases are closely related with the exception of gut microbes. With the probiotic preparations and fecal microbiota transplants widely accepted in the treatment of digestive diseases, intestinal microorganisms has become a hotspot in the modern researches. In this paper, the digestive system diseases related to gut microbes were reviewed, and brief introductions of fecal microbiota transplantation （ FMT） and traditional Chinese medicine （ TCM） regulating the intestinal micro ecology were also mentioned. The purpose is to attract the attention of the researchers in the gut microbes and the interaction between TCM and gut microbes.