临床药师干预对宫腔镜围术期抗菌药物使用的效果观察

Observation on the effect of clinical pharmacist intervention on the use of antibiotics in the perioperative period of hysteroscopy

目的探讨分析宫腔镜围术期临床药师干预抗菌药物使用的效果。方法在2016年11月~2017年4月于我院接受宫腔镜手术治疗的患者中选取符合条件的220例作为研究对象,并随机分为两组,其中110例患者使用抗菌药物接受临床药师干预,为观察组;另110例患者常规使用抗菌药物,无临床药师干预,为对照组。观察比较两组患者抗菌药物的使用率、药物选择合理率、用药疗程、用药疗程合理率等指标,分析宫腔镜围术期临床药师干预抗菌药物使用的效果。结果观察组患者抗菌药物使用率较对照组患者显著降低,差异有统计学意义(P<0.05);观察组患者药物选择合理率较对照组患者显著升高,差异有统计学意义(P<0.05);观察组患者平均用药疗程较对照组患者明显缩短,差异有统计学意义(P<0.05);观察组患者用药疗程的合理率较对照组患者显著升高,差异有统计学意义(P<0.05)。结论宫腔镜围术期临床药师干预抗菌药物使用,在一定程度上提高了药物选择合理率、用药疗程合理率,降低了抗菌药物使用率,值得临床运用和推广。

Objective To investigate the effect of clinical pharmacist intervention on the use of antibiotics during the perioperative period.Methods A total of 220 patients in our hospital were selected as the research object from November 2016 to April 2017,and were rangdomly divided into the following two groups.The observation group of 110 patients were treated with antibiotics for clinical pharmacist intervention,the control group were treated with conventionalantibiotics.The two groups of patients were observed and compared with the use rate of antimicrobial agents,the reasonable rate of drug selection,the reasonable rate of medication,and so on.Results The usage rate of antimicrobial drugs in the observation group was lower than that in the control group,the difference was statistically significant （P〈0.05）;the rate of rational drug selection in the observation groupincreased was higher than that the control group,the difference was statistically significant （P〈0.05）;the reasonable rate in the observation group was higher than that in the control group,the difference was statistically significant （P〈0.05）.Conclusion Hysteroscopy perioperative clinical pharmacist intervention the use of antibiotics can improve the rational drug selection rate,drug treatment and reasonable rates,reduce the use rate of antibacterial drugs,which is worthy of clinical application and promotion.