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非小细胞肺癌脑转移应用厄洛替尼联合全脑放射治疗的疗效评价

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摘要 目的探讨非小细胞肺癌(NSCLC)脑转移患者应用厄洛替尼联合全脑放射治疗的临床效果。方法选取医院接诊的非小细胞肺癌脑转移患者80例为研究对象,随机分为对照组与观察组,每组40例。对照组采用全脑放射治疗,观察组采用全脑放射治疗联合厄洛替尼治疗。观察记录2组患者的临床效果(总体缓解率)以及随访1年生存率、中位生存时间,并做对比分析。结果观察组总体缓解率为92.50%,高于对照组的75.00%,2组比较差异有统计学意义(P<0.05);观察组随访1年生存率与中位生存时间均大于对照组,2组比较差异有统计学意义(P<0.05)。结论非小细胞肺癌脑转移患者采取全脑放射治疗联合厄洛替尼治疗,不仅可以提高临床疗效,而且可以提高远期生存率,延长生存时间,值得临床推广应用。
作者 阳美玲
出处 《临床合理用药杂志》 2017年第23期44-45,共2页 Chinese Journal of Clinical Rational Drug Use
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