正交试验优选复方三匙饮提取工艺

Orthogonal Optimization of Extracted Technology of Compound San Chiyin

目的:优化壮药复方三匙饮的提取工艺条件。方法:以牛弥菜醇A的含量为指标,通过不同液料比,不同提取时间、不同提取次数,采用L9(34)正交试验,优选最佳提取工艺条件。结果:优选出的最佳提取工艺为采用14倍溶剂,水煎煮提取2次,每次40min。结论:优化壮药复方三匙饮的提取工艺稳定可行,有效成分提取率较高,适合大生产需求,可为壮药复方三匙饮制剂生产提供参考。

Objective To optimize the extraction technique conditions of the Compound San Chiyin. Methods Select the best ex- traction technique by using L9 （34 ） orthogonal test in different liquid - solid ratio, different extraction time and different extraction times, with the content of conduritol A as the index. Results The optimum extraction process was as follows 14 times amount of water, 40 minutes every time, 2 times of extraction. Conclusion The extraction technique of optimizing the compound was stable and feasible, the extraction rate of active ingredient is fairly high, it＇ s suitable and referable for large production needs.