贲门癌侵及食管下段患者术后胃食管反流的治疗研究

Treatment of gastroesophageal reflux after the operation of cardia cancer invading the lower esophagus

目的 探讨贲门癌侵及食管下段患者术后胃食管反流的治疗方法.方法 回顾性分析2013年1月至2015年12月,新疆维吾尔自治区人民医院胸外科行手术治疗的216例贲门癌侵及食管下段的患者临床资料,随访2~18个月（中位数8个月）,并观察恢复状况.结果 216例贲门癌侵及食管下段患者中,95例患者术后出现胃食管反流,其中26例患者反流症状较明显,经口服药物及行为干预治疗后患者胃食管反流症状均能得到缓解.结论 术中将胸胃缩小缝合形如食管,重建食管裂孔,能有效起到抗反流作用,结合术后药物及行为干预治疗,可以显著缓解贲门癌侵及食管下段患者术后胃食管反流的临床症状.

Objective To explore thecomprehensive treatment of gastroesophageal refluxafter theoperation of cardia cancer invading the lower esophagus. Methods Retrospective analysis the clinical data of 216 patients with carcinoma of the cardia and lower esophagus treated by thoracic surgery in the people＇shospital of Xinjiang Uygur autonomous region from January 2013 to December 2015reduced and sutured as esophagus, besides the esophagus crack hole was reconstructed in Postoperative comprehensive treatment was made for the patients with gastroesophageal reflux after surgery, and the recovery process was observed. Results After 6 months to 3 years following up postoperativpatients had mild reflux,26 patients had obvious reflux symptoms, and the symptoms were relievadministration of drugs and combined therapy. Conclusion In the operation, reducing the thoraand suturing it as esophagus, besides reconstructing the esophagus crack hole, reduce gastroesophageal reflux, combining with drug and intervention therapy can significantly relieve the clinical symptoms of patients.