海军某部高尿酸血症现况调查及危险因素分析

Investigation and analysis of risk factors of hyperuricemia in a certain navy unit

目的了解海军某部高尿酸血症的流行现状及其危险因素。方法整群抽取某部常驻官兵1 483名,利用问卷调查和血生化测定,调查某部高尿酸血症(HUA)的患病情况及危险因素。结果 (1)209人检出HUA,患病率为14.09%。低年龄组血尿酸含量显著低于高年龄组,干部血尿酸含量显著高于战士,差异有统计学意义(P<0.05);(2)每人每日运动量(OR=2.108,P<0.05)、出海连续航行天数(OR=2.317,P<0.05)、较高的体质量指数(BMI)(OR=1.483,P<0.05)、每日海鲜摄入量(OR=1.965,P<0.05)是发生HUA的危险因素。结论年龄较大、干部、低运动量、长期出海、较高的BMI、海鲜摄入过量等均是HUA的危险因素。调整饮食结构,降低嘌呤摄入量、减肥并加强体能锻炼是预防HUA的主要措施。

Objective To analyze prevalence and risk factors of hyperuricemia in a certain navy unit. Methods A total of 1483 commissioned and enlisted from a certain navy unit was selected for the study, and the prevalence and risk factors of hyperuricemia were investigated by questionnaire survey and blood biochemistry. Results （1） Two hundred and nine people had hyperuricemia, with an incidence of 14.09%. Serum urine acid level in the low-age group was significantly lower than that in the high-age group, and the blood urine acid level of commissioned officers was significantly higher than that of the sailors （P 〈0.05）. （2） Daily exercise intensity （OR = 2.108, P 〈 0. 05 ） , the number of days of deployment at sea （ OR = 2. 317, P 〈 0.05 ） , higher body mass index （ OR = 1.483 , P 〈0.05） and daily seafood intake （ OR = 1.965, P 〈0.05） were main risk factors of hyperuricemia. Conclusion High age, senior positions as cadres, low intensity of exercise, prolonged deployment at sea, higher BMI index, excessive intake of seafood were all risk factors of hyperuricemia. Adjustment of daily diet, lower level of purine, control of overweight, and more exercises for enhancement of physical performance were main countermeasures for the prevention of hyperuricemia.