多重耐药菌株在重症医学科感染监测中的分布及耐药情况分析

Analysis of Distribution and Drug Resistance of Multiple Resistance Strains in the Infection Monitoring in ICU

目的了解该院重症医学科多重耐药菌株(MDR)感染监测的分布及耐药情况。方法选取该院于2015年6月—2016年6月间收治的1 100例多重耐药菌个人患者,分离出其中的1 100株病原菌,其中673株来自于男性,427株来自于女性患者,对其进行常规分离培养鉴定,根据相关标准筛选出MDR并调查和分析MDR的感染情况,采取一系列预防感染的护理措施来降低MDR的感染率。结果 MDR菌株共有278株,占总分离病原菌的25.27%(278/1 100),大肠埃希菌中MDR最多,为112株(40.29%)。MDR多见于痰液中,其所占比例为43.52%(121/278),其次多见于中段尿,所占比例为21.94%(61/278)。2014年1月—2015年12月间ICU共入住患者2 444例,其中院内感染患者462例,其中多重耐药菌院内感染278例,医院感染病例中多重耐药感染占60.17%。结论多重耐药菌是ICU感染的主要致病菌,多重耐药菌患者感染部位主要以呼吸道为主,临床实践研究显示,通过合理的干预措施,可以有效降低其感染率。

Objective To know the distribution and Drug Resistance of multiple resistance strains in the infection monitoring in ICU. Methods 1 100 cases of patients with multiple resistance strains admitted and treated in our hospital from June 2015 to June 2016 were selected and 1 100 strains of pathogenic bacteria were isolated, and 673 strains came from male, while 427 strains came from females, and the strains were given the routine isolation and culture identification, and the MDR was screened according to the related standards and surveyed and the MDR infection was analyzed, the MDR infection rate was decreased by a series of preventive infection nursing measures. Results There were 278 MDR bacterial strains, accounting for 25.27% （278/1 100）, and the MDR was the most in E.col, accounting for 40.29% （112 strains）, and MDR was more common in sputum, accounting for 43.52%（121/278）, the second was in midportion urine, accounting for 21.94%（61/278）, from January 2014 to December 2015, 2 444 cases of patients were admitted in ICU, including 462 cases of hospital infection patients, and there were 278 cases of patients with muhidrug resistant bacteria hospital infection, accounting for 60.17%. Conclusion The multiple resistance strains are the major pathogenic bacteria in ICU infection, and the infection site of patients with multiple resistance is mainly respiratory tract, and the clinical practice research shows that the rational intervention measures can effectively reduce the infection rate.