静脉滴注丙种球蛋白治疗小儿重症肺炎的疗效分析

Analysis of Curative Effect of Intravenous Drip of Gamma Globulin in Treatment of Severe Pneumonia in Children

目的探讨丙种球蛋白静脉滴注治疗小儿重症肺炎的效果。方法选取该科2014年9月—2016年9月收治的166例小儿重症肺炎患儿,随机分为两组各83例,对照组给予常规综合治疗,观察组在对照组的基础上给予丙种球蛋白静脉滴注治疗,比较两组治疗效果。结果观察组总有效率为93.9%,显著优于对照组80.7%(P<0.05);观察组退热时间(2.1±0.9)d、咳嗽消失时间(4.2±1.3)d、气促消失时间(3.7±1.5)d、肺部啰音消失时间(3.9±1.2)d、胸部阴影吸收时间(5.7±2.1)d和平均住院时间(7.6±1.2)d,较对照组明显缩短(P<0.05)。结论丙种球蛋白静脉滴注可有效提高重症肺炎患儿治疗效果,促进临床症状消失,改善患儿预后,值得临床应用。

Objective To study the effect of intravenous drip of gamma globulin in treatment of severe pneumonia in children. Methods 166 cases of children with severe pneumonia treated in our hospital from September 2014 to September 2016 were selected and randomly divided into two groups with 83 cases in each, the control group adopted the routine comprehensive treatment, while the observation group adopted the intravenous drip of gamma globulin on the basis of the control group, and the treatment effect was compared between the two groups. Results The total effective rate in the observation group was obviously better than that in the control group（93.9% vs 80.7%）, and the defervescence time, cough disappearance time, panting disappearance time and lung rales disappearance time, chest spot absorption time and average length of stay in the observation group were respectively（2.1±0.9）,（4.2±1.3）,（3.7±l.5）, （3.9±± 1.2）, （5.7±2.1）d and （7.6±1.2）d, which were obviously shortened compared with those in the control group （P〈0.05）. Conclusion The intravenous drip of gamma globulin can effectively improve the treatment effect of children with severe pneumonia, promote the disappearance Of clinical symptoms and improve the prognosis of children, which is worth clinical application.