Westerhof阻力器计算阻值的一种校正方法

A correction method for calculating resistance of Westerhof 's resistor

人体血液模拟循环系统(MCS)的目标是重现心血管血流动力学的特性。Westerhof阻力器在MCS中担任层流液阻器的角色,用来模拟心血管系统的外周阻力。Westerhof阻力器的理论计算结果较实际的液阻值有较大的误差,如果将理论公式计算的液阻值当作实际的液阻值,那么精确度明显达不到设计目标和性能要求。为了减少阻力器液阻值理论计算结果与实际值之间的误差,本文提供了一种有效的Westerhof阻力器计算阻值的校正方法,并且开发了仿真模拟软件。仿真软件可以较为准确地预测毛细管数量、总长度、液阻值,降低和简化了设计阻力器的难度和复杂度,使得Westerhof阻力器制作更为精准,为各种循环模拟系统的构建提供了支持。

The objective of the mock circulatory system （MCS） is to construct the characteristics of cardiovascular hemodynamics. Westerhof＇s resistor that often regarded as the laminar flow resistance in the MCS, is commonly used to simulate the peripheral resistance of the cardiovascular system. However, the theoretical calculation value of fluid resistance of the Westerhof＇s resistor shows distinguished difference with the actual needed value. If the theoretical resistance is regarded as the actual needed one and be used directly in the experiment, the experimental accuracy would not be acceptable. In order to improve the accuracy, an effective correction method for calculating the resistance of Westerhof＇s resistor was proposed in this paper. Simulation software was also developed to compute accurately the capillary number, total length and resistance. The results demonstrate the proposed method is able to reduce the difficulty and complexity of the design of the resistor, which would obviously increase the manufactured precision of the Westerhof＇s resistor. Simulation software would provide great support to the construction of various MCSs.