一种速干手消毒剂使用效期及消毒效果观察

Observation on expiration date and disinfectant efficacy of an alcoholbased hand disinfectant

目的了解速干手消毒剂启用后的有效期,为临床合理使用速干手消毒剂提供参考依据。方法选取某院手卫生依从性排名后4位的临床科室同一时间开启使用的20瓶某品牌速干手消毒剂为研究对象,开启使用后第1天采样,每10 d重复采样直至消毒剂使用完为止。同时对使用相应消毒剂消毒的手采样。检测消毒剂和手标本合格情况。结果共采集消毒剂样本98份,经肉眼观察,整个研究期间20瓶速干手消毒剂无变色、沉淀、悬浮物等。速干手消毒剂开瓶后60 d内检测合格率均为100%。共采集消毒后手标本44份,其中有3份标本检测不合格,均为使用开启后第50天的速干手消毒剂,检测不合格人员使用同批次速干手消毒剂后进行二次采样,检测合格,考虑不合格原因非消毒剂本身影响。结论含醇速干手消毒剂在开启后第60 d仍具有良好的杀菌作用。

Objective To understand the expiration date of alcohol-based hand disinfectant after it is opened for use, and provide reference for rational clinical application of alcohol-based hand disinfectant. Methods 20 bottles of the same brand alcohol-based hand disinfectant which opened at the same time by the clinical departments were selected as the study object, hand hygiene compliance in theses departments ranked fourth from the end in the hospital, specimens were taken on the first day after opening, and repeated every 10 days until the disinfectant was used up. Hand specimens were also taken after disinfected by disinfectant. Qualified condition of disinfectant and hand specimens was detected. Results A total of 98 disinfectant specimens were collected, by naked eye observation, 20 bottles of alcohol-based hand disinfectant were free of discoloration, precipitation, and suspended matter during the whole study period. The qualified detection rates of alcohol-based hand disinfectant within 60 days after opening were all 100%. 44 hand specimens were taken and detected after disinfection, 3 of which were unqualified （all were disinfected by alcohol-based hand disinfectant 50 days after opening）, then detected again after disinfected by the same batch of disinfectant, all were qualified, which suggested that unqualified detection result of hand specimens was not due to disinfectant. Conclusion Alcohol-based hand disinfectant still has a good bactericidal effect on the sixth day after opening.