心房颤动的基因学研究进展

An update on genetic research of atrial fibrillation

心房颤动基因学研究包括以下几个于临床有意义的话题:(1)单/多基因心房颤动的分子遗传变异;(2)心房颤动的合理分类;(3)心房颤动家族聚集的遗传学原因;(4)基因型差异对心房颤动预后的影响及其风险预测;(5)心房颤动的治疗基因学。该文将对以上问题逐一作出论述。

Genetic researches of atrial fibrillation（ AF） include the following topics which are important in clinical practice：（1）the molecular genetic variations of mono/polygenic AF;（2）the reasonable classification of AF based on genetics;（3） the underlying genetic reasons of its familial segregation;（4） the impact of genotype difference on prognosis of patients with AF and AF risk prediction;（5）the genetic studies on AF treatment. This review is an update on the abovementioned issues.