孟鲁司特钠辅助治疗婴幼儿毛细支气管炎的效果观察

Effect observation of montelukast sodium in the adjuvant treatment of infants with bronchiolitis

目的研究孟鲁司特钠辅助治疗婴幼儿毛细支气管炎的效果。方法收集我院2012年1月至2015年1月收治的120例婴幼儿毛细支气管炎患者临床资料,按照治疗方法将120例患儿分为观察组和对照组,每组60例。对照组患儿采用常规的综合性治疗,在此基础上观察组患儿采用孟鲁司特钠进行辅助治疗。观察两组患儿的临床治疗效果和复发情况。结果观察组患儿治疗总有效率为95.00%(57/60),明显高于对照组患儿的71.67%(43/60),差异有统计学意义(P<0.05);观察组患儿的症状复发率为6.67%(4/60),对照组的症状复发率为18.33%(11/60),观察组症状复发率低于对照组(P<0.05)。结论孟鲁司特钠辅助治疗婴幼儿毛细支气管炎能够取得较好的临床效果,患儿复发率低,可在临床应用推广。

Objective To study the effect of montelukast sodium in the adjuvant treatment of infantile bmnchiolitis. Methods The clinical data of 120 cases of children with bronchiolitis treated in our hospital from Jannuary 2012 to Jan- nuary 2015 were selected, and the children were divided into observation group and control group according to treatment methods, with 60 cases in each group. The control group was treated with conventional comprehensive treatment, on this basis, the observation group accepted montelukast sodium adjuvant therapy. The therapeutic effects and recurrence rate of the two groups were compared. Results The total effective rate of the observation group was 95.00% （57/60）, which was significantly higher than 71.67% （43/60） of the control group, the difference was statiatically significant （P〈0.05）. The symptom relapse rate of the observation group was 6.67% （4/60）, of the control group was 18.33% （11/60）, the symptom relapse rate of the observation group was lower than the control group, the difference was statistically significant （P〈0.05）. Conclusion Montelukast sodium can be used as an adjunctive therapy for children with bronchiolitis, with low relapse rate, which can be popularized in clinic.