摘要
目的 :探讨中药火硝治疗结石的作用机理。方法 :基于古今中医临床实践 ,借鉴现代化学动力学、生理学等基础知识。结果 :火硝能影响 K+ - Na+ 交换与 H+ - Na+ 交换 ,使尿 K+ 与 H+ 交互升高 ,清除尿素 ,减轻尿路损伤 ,抑制结石基质形成 ,产生盐效应和利尿效应等。结论 :火硝具有抑制结石基质形成、促进结石溶解、增强结石排出动力 ,即抑石、溶石。
Objective:To investigate the mechanism of Potassium Nitrate treating concretion.Methods:On the basis of clinical practice of ancient and modern TCM, using the elementary knowledge of modern chemistry and physiology.Results:Potassium nitrate can influence the exchange of K +-Na + and H +-Na +, make the exchange of K +-H + rising, clear away the urea, reduce damage of urethra, inhibit the formation of concretion base, produce salt and diuresis effect.Conclusion:Potassium nitrate has the effect of inhibiting the formation of concretion base, promoting the dissolve of concretion, increasing the impetus of removing the concretion.
出处
《时珍国医国药》
CAS
CSCD
2002年第9期523-524,共2页
Lishizhen Medicine and Materia Medica Research
关键词
中药药理
火硝
泌尿系结石
Chinese traditional medicine
Pharmacology
Potassium nitrate
Concretion
