温州市犬狂犬病免疫情况调查

Investigation on Immune Status of Rabies in Dogs in Wenzhou

为了解浙江省温州市犬狂犬病免疫情况,采用酶联免疫吸附试验,检测351份血浆样本中的狂犬病病毒IgG抗体。结果显示,该地区犬狂犬病病毒IgG抗体阳性率为46.44%(163/351);雄犬抗体阳性率略高于雌犬(P>0.05),已进行绝育/去势术的犬阳性率极显著高于未进行绝育/去势术的犬(P<0.01);成年犬的抗体阳性率极显著高于幼年犬(P<0.01)和老年犬(P<0.01);家养宠物犬的抗体阳性率极显著高于训导场内的犬(P<0.01)和流浪犬(P<0.01)。综上提示,温州地区犬狂犬病病毒IgG抗体阳性率相对处于中等水平,应进一步加强对流浪犬和训导场内犬的管理,扩大犬的免疫覆盖率,以控制该地区狂犬病的传播。

In order to determine the seroprevalence of rabies virus among dogs in Wenzhou of Zhejiang Province, plasma samples of 351 dogs were tested forIgG antibodies against rabies virus by ELISA. The results revealed that rabies virus IgG antibodies were detected in 163（46.44%） of the 351 dogs; male dogs had slightly higher antibodies positive rate compared to female ones（P〉0.05）, and the seroprevalence was extremely significantly higher in neutered dogs than intact dogs（P〈0.01）; extremely significantly higher seroprevalence was observed in adult dogs compared to young（P〈0.01） and geriatric dogs（P〈0.01）; the seroprevalence in household dogs was extremely significantly higher than dogs in training field（P〈0.01） and stray dogs（P〈0.01）. The combined data suggest that the rabies virus prevails in dogs at a moderate level in Wenzhou, the management of dogs in training field and stray dogs should be enhanced, and the immunization coverage against rabies virus for dogs should be extended, so as to control the spread of rabies in this region.