工作场所空气中正丙醇测定方法研究

Study on method for determination of n-Propanol in the air of workplaces

[目的]研究并建立适用于工作场所空气中正丙醇的定量检测方法。[方法]工作场所空气中正丙醇由活性炭管采集,经体积比为1∶100的异丙醇-二硫化碳混合溶剂解吸后,经石英弹性毛细管柱HP-INNOWAX(30.0 m×0.53 mm×1.0μm)分离,氢焰离子化检测器检测,标准曲线法定量。[结果]正丙醇浓度在10~500μg/m L范围内和峰面积呈线性关系,回归方程y=2.12 x+1.96,相关系数r=0.999 9(P<0.05)。以3.0 L采样量计,方法最低检出浓度0.09 mg/m3,最低定量浓度0.30 mg/m3;不同浓度加标样品测定结果的相对标准偏差为1.7%~3.6%,解吸效率89.3%~94.7%,采样效率>96%,100 mg活性炭对正丙醇的穿透容量为16 mg;采样后的活性炭管在室温条件下至少可放置7 d。[结论]建立的工作场所空气中正丙醇溶剂解吸-气相色谱测定方法准确可靠、灵敏度高、稳定性良好,适用于工作场所空气中正丙醇的现场检测。

[Objective] To establish a method for the quantitative determination of n-propanol in the air of workplaces. [Methods] The charcoal tubes were used for collection of airborne n-propanol in workplaces, and the 1% isopropanol-carbon disulfide mixture solvent was used for desorption. The analytes were separated with capillary column HP-INNOWAX （30.0 m x 0.53 mm x 1.0 μm）,then detected with FID and quantified with standard curve method. [Results] The liner range of n- propanol concentrations was 10 to 500 mg/L with the regression equation y = 2.12 x ＋ 1.96 ,and the con：elation coefficient（r） was 0.999 9 （P 〈 0.05）. The limit of quantitation （LOQ） of n-propanol in air was 0.30 mg/m3 and the concentration of analytes in air was 0.09 mg/m3 based on the sampling volume （3.0 L）. The relative standard deviations （RSD） varied from 1.7% to 3.6%. The desorption efficiencies varied from 89.3% to 94.7% and the sampling efficiency was more than 96%. The breakthrough volume was 16 mg of n-propanol in 100 mg of active carbon. The activated carbon tubes after sampling can be stored at room temperature for 7 days. [Conclusion] This method applied solvent desorption with gas chromatographic method for determination of n-propanol in the air of workplaces was of high sensitivity, and good stability, which is appropriate for the field monitoring of n-propanol in the air of workplaees.