除痹丸的制备及主要成分的薄层色谱鉴别

Preparation of Chubi pill and the thin layer chromatography of its main ingredient

目的确定除痹丸制备工艺及建立质量控制标准。方法采用泛制法工艺及薄层色谱法对除痹丸处方中君药黄芪、白术以及臣药葛根进行定性鉴别。结果该法丸粒均匀、圆整、光洁,溶散时限快,丸重差异小;供试品薄层色谱鉴别斑点清晰,重现性好,阴性对照无干扰。结论除痹丸所用制备工艺简便易控,质量控制准确易操作,产品稳定性好。

Objective To determine the preparation technology of Chubi pill and establish its quality control standard. Methods The pan-method and thinlayer chromatography were used to qualitatively identify the prescriptions of the sovereign drug Astragalus and Atractylodes, ministerial drug Puerarin in Chubi pill. Results Of this method, the pellets were uniform, round and smooth, the dissolution time was fast and the difference was small; the identify spots of specimen with thin layer chromatography was clear, with good reproducibility, and the negative control was not interfered. Conclusion The preparation process of Chubi pill is simple and easy to control, the quality control is accurate and easy to operate, with good production stability.