视网膜血管增生样瘤特征和治疗分析

The clinical features and curative effects of vasoproliferative retinal tumor

目的分析视网膜血管增生样瘤的临床表现特征，探讨临床治疗方法及临床疗效。方法回顾性分析北京大学人民医院2005年10月至2015年2月收治的视网膜血管增生样瘤患者21例（22只眼），根据B超检查结果和眼底荧光素血管造影针对性治疗，分析患者的临床治疗效果及并发症的发病情况。结果21例患者在分别接受相应玻璃体腔注抗VEGF、放射敷贴、视网膜冷冻、激光光凝、玻璃体手术切除治疗后，患者的眼底渗出减少，肿瘤缩小，临床治疗有效率分别为50.00%、50.00%、66.67%、83.33%、77.78%，激光光凝和玻璃体手术切除治疗的疗效明显高于其他3种治疗方法，且差异有统计学意义（P〈0.05）。结论激光光凝和玻璃体切除手术治疗可以有效改善缩小肿瘤，减少渗出，消退水肿，具有良好的安全性和稳定性，值得在临床应用。

Objective To visualize the clinical features and investigate the major treatments and clinical curative effects of vasoproliferative retinal tumor. Methods In these retrospective case series, 21 patients （22 eyes） were selected who were diagnosed as vasoproliferative retinal tumor between October 2005 and February 2015. The patients manifested as hemorrhage before or in the retinal. The patients were treated by different surgeries on the bases of ocular examinations such as B ultra-scan and fundus fluorescein angiography. Results Patients who were treated by intravitreal injection, radiation application, retinal freezing, laser photocoagulation or vitrectomy gained less fundus exudation and contraction tumors, with efficiencies of 50.00%, 50.00%, 66.67%, 83.33% and 77.78% respectively. Among which the effective rate of laser photocoagulation and vitrectomy were apparently higher than other therapies. Conclusions Photocoagulation and vitrectomy are good for the regression of vasoproliferative retinal tumor and can be applied clinically.