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STK11基因的研究进展

Advances in the research on the STK11 gene
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摘要 STK11基因是最近发现的一种肿瘤抑制基因 ,定位于人类染色体 19p13.3区。其基因产物是丝氨酸-苏氨酸蛋白激酶的一种 ,与细胞的生长增殖等行为有重要的关系 ,并且可能在细胞凋亡中起重要作用。但该基因的作用机制还不甚清楚 ,亟待进一步深入研究。 STK11 gene is a recently found tumor suppressor gene. It maps 19p13.3. This gene can express a kind of serine threonine kinases. STK11 gene plays an important role in the regulation of cell cycle progression, and it may relate to cell apoptosis. However, until now the mechanisms of STK11 gene is not very clear and progress in the research of this new tumor suppressor gene is sitll needed.
作者 沈赞 邵志敏 沈镇宙
机构地区 复旦大学附属肿瘤医院乳腺外科
出处 《中国癌症杂志》 CAS CSCD 2002年第4期361-363,共3页 China Oncology
关键词 研究进展 STK11基因 PEUTZ-JEGHERS综合征 抑癌基因 乳腺癌 gene,STK11 Peutz Jephers syndrome tumor suppressor gene breast cancer
分类号 R596.1 [医药卫生—内科学] R737.9 [医药卫生—肿瘤]
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参考文献14

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中国癌症杂志
2002年 第4期

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