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培美曲塞单独治疗肺大细胞癌临床疗效观察

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摘要 目的观察培美曲塞单独治疗肺大细胞癌的临床效果。方法将92例肺大细胞癌患者随机分为观察组和对照组各46例。观察组给予培美曲塞治疗,对照组给予多西他赛治疗。比较2组患者的临床治疗有效性、疾病控制率及不良反应发生率。结果观察组总有效率为52.17%高于对照组的28.26%,差异有统计学意义(P<0.05);观察组控制率为86.96%,对照组为84.78%,差异无统计学意义(P>0.05);观察组不良反应总发生率为10.87%低于对照组的28.26%,差异有统计学意义(P<0.05)。结论多西他赛以及培美曲塞虽然均能够实现对肺大细胞癌患者病情的有效控制,但培美曲塞具有更高的临床治疗有效性,并且具有更低的药物不良反应发生率。
作者 李山河
出处 《临床合理用药杂志》 2017年第16期69-70,共2页 Chinese Journal of Clinical Rational Drug Use
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