右美托咪定对小儿七氟醚麻醉后苏醒期躁动的预防效果

Prevention effect of dexmedetomidine on agitation in awakening period after pediatric sevoflurane anesthesia

目的探讨右美托咪定对小儿七氟醚麻醉后苏醒期躁动的预防效果。方法选取射阳县人民医院2014年1月—2016年10月收治的行扁桃体、腺样体肥大切除术患儿70例,按照随机数字表法分为对照组和观察组,各35例。患儿均采用七氟醚吸入诱导麻醉,手术期间,对照组患儿给予0.9%氯化钠溶液,观察组患儿给予盐酸右美托咪定注射液。比较两组患儿苏醒期RSAS评分及不良反应发生情况。结果观察组患儿苏醒期RSAS评分、不良反应发生率低于对照组(P<0.05)。结论右美托咪定在小儿七氟醚麻醉后苏醒期躁动中具有预防和控制作用,且安全可靠。

Objective To investigete the prevention effect of dexmedetomidine on agitation in awakening period after pediatric sevoflurane anesthesia. Methods A total of 70 cases of children underwent tonsillitis and adenoid hypertrophy resection were selected from January 2014 to October 2016 in Sheyang County People＇ s Hospital,which were divided into control group and observation group according to random number table,35 cases in each group. All children were given inhalation sevoflurane induced anesthesia,during surgery,control group was given 0. 9% sodium chloride solution,observation group was given dexmedetomidine hydrochloride injection. The RSAS scores in awakening period and the incidence of adverse reactions were compared between the two groups. Results During the awakening period,the observation group of RSAS scores and adverse reactions rate were lower than control group（ P〈0. 05）. Conclusion Dexmedetomidine has the function of prevention and control on agitation in awakening period after pediatric sevoflurane anesthesia,and it is safe and reliable.