布蓝合剂用于混合痔术后镇痛的临床观察

Clinical observation on postoperative analgesia effect of Bupivacaine Methylene blue mixture used for mixed hemorrhoid

目的探讨布蓝合剂应用于混合痔术后镇痛的效果。方法选取本院治疗182例混合痔患者为研究对象,随机分成观察组(n=92)及对照组(n=90),均行混合痔外剥内扎术。观察组手术结束时,创缘注射布蓝合剂;对照组采用经静脉自控镇痛泵(PCIA)术后镇痛。比较两组术后疼痛评分、术后镇痛药使用率以及不良反应总发生率。结果观察组术后6 h、12 h、24 h、48 h的疼痛评分较对照组低(均P<0.05);观察组术后镇痛有效率高于对照组(P<0.05),术后镇痛药使用率及不良反应总发生率均低于对照组(均P<0.0)。结论布蓝合剂用于混合痔术后镇痛效果良好,不良反应少,是一种经济有效、操作简单的术后镇痛方法。

Objective To study the effect of Bupivacaine Methylene blue mixture in postoperative analgesia in mixed hemorrhoid.Methods 182 hospitalized cases of mixed hemorrhoid were recruited as study subjects. 92 cases were randomly assigned to treatment group and 90 cases to control group. All patients underwent traditional haemorrhoidectomy treatment. At the end of the surgery,in treatment group,the wound margin was injected with Bupivacaine Methylene blue mixture. The control group was given pain-controlled analgesic pump（PCIA） after the operation. The postoperative pain scores,the use of analgesics and the total incidence of adverse reactions were compared between the two groups. Results The pain scores of 6 h,12 h,24 h and 48 h in the treatment group were lower than those in the control group（P〈0. 05）. Postoperative analgesia efficiency in observation group of is higher than in the control group（P〈0. 05）. Postoperative analgesic usage and the incidence of adverse reactions in the treatment group was lower than the control group（all P〈0. 05）. Conclusion Bupivacaine Methylene blue mixture is an effective method for the postoperative analgesia.