摘要
目的:研究中药原料在不同温湿度条件下的吸湿行为。方法:应用膜扩散传质模型和菲克第二定律传质模型模拟和分析水分在中药原料中的扩散行为。结果:在25℃,相对湿度为50%时研究的13种中药原料的扩散系数最大,且扩散符合膜扩散传质过程。在其他温湿度环境下可能同时存在两种扩散机制。结论:水分在中药原料中的扩散可能存在多种扩散机制,并受环境因素影响明显。
This paper was aimed to study the moisture adsorption of Chinese herbal medicine ingredients at different environment. The film mass transfer model and Fick's second law were applied to evaluate the moisture diffusion for Chinese herbal medicine ingredients. The results showed that under the temperature of 25℃ and 50% relative humidity, the diffusion coefficient of 13 medicine ingredients reached the highest. The diffusivity was controlled by film mass transfer. However, both film mass transfer and Fick's second law can be existed at the same time under different temperature and humidity. It was concluded that the diffusion of water in the traditional Chinese medicine might have been driven by a variety of diffusion mechanism, which was obviously affected by environmental factors.
作者
赵立杰
王优杰
冯怡
杜若飞
Zhao Lijie Wang Youfie Feng Yi Du Ruofei(Engineering Research Center of Modern Preparation Technology of Traditional Chinese Medicine, Ministry of Education, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China)
出处
《世界科学技术-中医药现代化》
CSCD
2017年第4期686-693,共8页
Modernization of Traditional Chinese Medicine and Materia Medica-World Science and Technology
基金
上海市卫计委科研项目(ZY3-CCCX-3-5001):中药制剂关键技术研究与应用
负责人:冯怡
上海市科委平台资助项目(15DZ2292000):上海市中药固体制剂专业技术服务平台
负责人:冯怡
国家自然科学基金委青年科学基金项目(81403110):基于人工神经网络算法的中药硬胶囊剂设计原理研究
负责人:杜若飞
国家自然科学基金青年科学基金项目(81503263):羟丙基甲基纤维素改善中药喷雾干燥热熔型黏壁及其机理研究
负责人:王优杰
上海市教育委员会预算内项目(2014YSN23):固体中药制剂原料吸湿行为模拟与分析
负责人:赵立杰
关键词
吸湿
扩散
膜扩散
菲克第二定律
Moisture adsorption, diffusivity, film mass transfer, Fick's second law