期刊文献+

2型糖尿病患者视网膜病变易感因素分析

下载PDF
导出
摘要 目的探讨2型糖尿病患者视网膜病变(CR)易感因素。方法收集200例2型糖尿病患者住院病历资料,分析可能引起糖尿病视网膜病变(DR)发生的相关易感因素。结果 200例患者其中DR 78例、非DR 122例,DR患病率为39.00%,DR中单纯型56例、增殖型22例,分别占71.79%、28.21%;单因素分析患者年龄、病程、收缩压、舒张压、空腹血糖、糖化血红蛋白、低密度脂蛋白、血浆粘度、全血高切粘度、全血低切粘度与DR发生有关(P<0.01),BMI、总胆固醇、甘油三酯、高密度脂蛋白、载脂蛋白A和B均与DR发生无关(P>0.05);多因素Logistic回归分析显示病程、空腹血糖、糖化血红蛋白、收缩压及舒张压是引起DR发生的独立危险因素(P<0.05或P<0.01)。结论 2型糖尿病患者病程长、血糖控制不佳、合并高血压是引起DR发生的易感因素,应针对以上易感因素进行积极干预以预防及降低DR发生。
出处 《白求恩医学杂志》 2017年第4期488-489,共2页 Journal of Bethune Medical Science
  • 相关文献

参考文献5

二级参考文献53

  • 1李慧,纪立农.新诊断2型糖尿病和糖尿病前期人群中糖尿病视网膜病变患病率及危险因素分析[J].中国糖尿病杂志,2007,15(7):387-389. 被引量:22
  • 2周新,涂植光.临床生物化学和生物化学检验[M].北京:人民卫生出版社,2002:83.
  • 3Engelgau MM, Thompson TJ, Herman WH, et al.Comparison of fasting and 2-hour glucose and HbAlc levels for diagnosing diabetes. Diagnostic criteria and performance revisited [J ] .Diabetes Care,1997,20(5):785-791.
  • 4Goldstein DE, Blinder KJ, Ide CH, et al. Glycemic cont rol and development of retinopathy in youth-onset insulin dependent diabetes mellitus: results of 12-years longitudinal study [J]. Ophthalmology, 1993 ,100: 1125-ll32.
  • 5Wilkinson CP , Ferris FL 3rd, Klein RE, et al.Proposed international clinical diabetic retinopathy and diabetic macular edema disease severity scales [J]. Ophthalmology, 2003, 110 (9) : 1677-1682.
  • 6Kullberg CE, Abr ahamsson M, Arnqv isl HJ, et al. Prevalence of retinopathy differs with age at onset of diabetes in a population of patients with Type 1 Diabetes [J]. Diabet Med, 2002, 19 (l1) :924.
  • 7Kim J, Kim KS, Shinn JW, et al. The effect of antioxidants on glycated albumin-induced cytotoxicity in bovine retinal pericytes [J].Biochem Biophys Res Commun,2002,292(4): 1010-1016.
  • 8Okudaira M, Yokoyama H, Otani T, et al.Slightly elevated blood pressure as well as poor metabolic control are risk factors for the progression of retinopathy in early-onset Japan type 2 diabetes[J].Diabetes Complications, 2000, 14 (5) : 281-287.
  • 9Zheng YF, He MG, Congdon Nathan.The worldwide epidemic of diabetic retinopathy [J]. Indian J Ophthalmol, 2012, 60 (5) : 428-431.
  • 10Ejaz S,Chekarova I,Ejaz A,et al. Importance of pericytes and mechanisms of pericyte loss during diabetes retinopathy[J]. Dia- betes Obes Metab, 2008,10( 1 ) : 53-63.

共引文献6827

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部