高压氧联合药物治疗脑梗塞的效果探讨

Effect of Hyperbaric Oxygen Combined with Drugs in the Treatment of Cerebral Infarction

目的探讨高压氧联合药物治疗脑梗塞的效果。方法选取2013年3月—2015年4月该院神经内科收治的80例脑梗塞患者作为研究的对象,按照不同的治疗方式将患者分为对照组和观察组,各40例患者,对照组给予单纯的药物治疗,观察组患者给予高压氧联合药物治疗,观察两组患者治疗前后NIHSS评分与Barthel指数、血液流变学相关指标以及梗塞面积。结果与对照组治疗后NIHSS评分与Barthel指数相比,观察组NIHSS评分(12.32±4.23)分与Barthel指数(76.35±9.87)分具有明显优势,差异具有统计学意义(P<0.05)。治疗后,观察组患者的血浆黏度(1.63±0.11)m Pa/s、HCT指标(48.52±6.56)%、红细胞聚集指数(2.93±0.52)以及FIB(1.93±0.62)g/L明显下降,与对照组相比具有显著优势,P<0.05,差异具有统计学意义。与治疗后对照组梗塞面积相比,观察组具有明显的优势,P<0.05,差异有统计学意义。结论高压氧联合药物治疗脑梗塞能够促进患者神经功能的恢复,改善患者的血液流变学指标,提高患者的生活质量。

Objective To explore the effect of hyperbaric oxygen combined with medicine in the treatment of cerebral infarction. Methods 80 patients with cerebral infarction in hospital from March 2013 to April 2015 were selected,80 patients were randomly divided into study group（40cases） and control group（40 cases）,study group patients were taken trentment of drug therapy, control group patients were taken trentment of high pressure oxygen combined with drug therapy,the NIHSS score, Barthel index, blood rheology indexes and infarct area of patients were compared. Results After treatment, The NIHSS score（12.32±4.23）points and Barthel index（76.35±9.87）points of the observation group had obvious advantage, and the difference was statistically significant（P 0.05）.The plasma viscosity（1.63 ±0.11）m Pa/s,HCT index（48.52±6.56）%, erythrocyte aggregation index（2.93±0.52） and FIB（1.93±0.62）g/L in the observation group were significantly decreased,Compared with the control group, the observation group had a significant advantage, P 0.05, the difference was statistically significant.The infarct area of the observation group had obvious advantages, P 0.05, the difference was statistically significant. Conclusion Hyperbaric oxygen combined with drug treatment of cerebral infarction can promote the recovery of neurological function, improve the patient＇s hemodynamics, improve the quality of life of patients.