联合熊去氧胆酸治疗胆汁反流性胃炎的疗效分析

Analysis of Curative Effect of Ursodeoxycholic Acid in the Treatment of Bile Reflux Gastritis

目的分析胆汁反流性胃炎行熊去氧胆酸联合疗法的效果。方法调查对象于2012年4月—2015年9月该院收治胆汁反流性胃炎患者中抽选,将80例按照入院的先后顺序分成不同疗法组,每组40例,其中对照组患者行多潘立酮、奥美拉唑疗法,研究组患者则行多潘立酮、奥美拉唑、熊去氧胆酸疗法,治疗结束后评定效果。结果研究组患者疾病治疗后病症缓解者38例,占比95.0%,和对照组缓解率的75.0%相比,差异有统计学意义(P<0.05);研究组患者疾病治疗后的腹胀、腹痛、呕吐等症状积分和对照组相比,差异有统计学意义(P<0.05);研究组患者疾病治疗后的并发症率、复发率和对照组相比,差异有统计学意义(P<0.05)。结论临床胆汁反流性胃炎患者行多潘立酮、奥美拉唑疗法上加用熊去氧胆酸作用突出,可加快症状消退速度,预防并发症及病症复发,提高病症效果,值得学习。

Objective To analyze the effect of bile reflux gastritis for ursodeoxycholic acid therapy. Methods The survey in2012 April- 2015 September in our hospital bile reflux gastritis patients lottery, 80 patients in accordance with the order of admission into different treatment groups of 40 patients in the control group in which patients domperidone, omeprazole therapy study patients Travelling domperidone, omeprazole, ursodeoxycholic acid therapy, after the end of treatment effect assessed. Results After the treatment of disease of patients symptoms relief in 38 cases, accounting for 95.0%, and the control group remission rate of 75.0% compared, P〈0.05, there is a difference between; study group patients after abdominal distension, abdominal pain, vomiting and other symptoms and control group compared, P〈0.05, there is a difference between; rate of study group patients after the treatment of complications, recurrence rate and control group compared, P〈0.05, differentiated. Conclusion Clinical bile reflux gastritis were treated with domperidone and omeprazole therapy with ursodeoxycholic acid effect prominent, speed up the symptoms subside speed, prevent the complications and the recurrence of disease, improve the effect of disease, it is worth learning.