老年人健康体检中的应用联合检测肿瘤标志物的效果分析

Analysis of the Effect of Combined Detection of Tumor Markers in the Health Examination of the Elderly

目的探讨肿瘤标志物联合检测在老年人健康体检中的效果。方法对2012年8月—2015年8月于河南省郑州大学第五附属医学进行健康体检的4 856例老年人的12种肿瘤标志物蛋白芯片的检测结果进行分析。结果4 856名老年人中,肿瘤标志物阳性人数108例(2.22%),单一指标阳性89例(1.83%),2个以上指标组合阳性19例(0.39%)。108例中男性55例(1.13%),女性53例(1.09%),男女例数差异无统计学意义(P>0.05);男性46例单一阳性,其中CEA阳性35例(76.09%),女性43例单一阳性,其中CA125阳性22例(51.16%)。结论在老年人健康体检中应用多种肿瘤标志物联合检测敏感性高,检出率高,方法可靠,在无症状老年人早期健康体检肿瘤筛查中值得推广应用。

Objective To explore the effect of tumor markers combined detection in the health examination of the elderly. Methods The detection the results of 12 tumor markers protein chip were analyzed in 4 856 elderly patients in our hospital from August 2015 to August 2012. Results 4 856 seniors, tumor marker positive number 108 cases（2.22%） and single index positive in 89 cases（1.83%）, the above two indicators combination was positive in 19 cases（0.39%） building 55 males（1.13%）, female 53 cases（1.09%）, the difference of the number of men and women had no statistical significance（P 〉0.05）; male 46 cases of single positive, the CEA was positive in 35 cases（76.09%）, women in 43 cases of single positive. The CA125 was positive in 22 cases（51.16%）. Conclusion In the elderly health examination in the application of a variety of tumor markers combined detection of high sensitivity, high detection rate, the method is reliable, in the asymptomatic elderly patients with early health examination tumor screening is worthy of popularization and application.