祛风宣肺、养阴润燥法治疗慢性咳嗽临床研究

Clinical Study on treatment of chronic cough with Qufeng Xuanfei and Yangyin Runzao method

目的探讨祛风宣肺、养阴润燥法治疗慢性咳嗽的临床疗效以及对血常规、肝肾功能、心电图安全性的观察。方法将30例慢性咳嗽病例选用桑叶、杏仁、浙贝母、前胡、蝉蜕、南沙参、麦冬、僵蚕、乌梅等组成的观察方治疗2周,观察咳嗽、咯痰等临床指标变化情况及血常规、尿素氮、肌酐、谷丙转氨酶、谷草转氨酶、心电图等安全性指标的变化情况。结果咳嗽的有效率为100%,咯痰的有效率为90.00%,总有效率为91.43。安全性指标:血常规、尿素氮、肌酐、谷丙转氨酶、谷草转氨酶及心电图治疗前后无统计学意义。结论祛风宣肺,养阴润燥法治疗慢性咳嗽的临床安全性可靠,疗效明显。

Objective To explore the clinical efficacy of Qufeng Xuanfei and Yangyin Runzao methods for the treatment of chronic cough, and the observation of blood routine, liver and kidney function, ECG safety. Methods To select 30 people with chronic cough, take the investigational drug including Sangye, Xingren, Zhebei, Qianhu, Chantui, Nanshashen, Maidong, Jiangcan, Wumei and so on. They take the investigational drug for 2 weeks, then observe the change of clinical index, such as cough, sputum, and the change of safety index, such as blood routine. Urea nitrogen, creatinine, alanine aminotransferase, aspartate aminotransferase, ECG safety index. Results Effective rate of cough is 100%, effective rate of expectoration is 90%, total effective rate is 91.43%. The safety indicators： blood routine, urea nitrogen, creatinine, alanine aminotransferase, aspartate aminotransferase, ECG before and after treatment no difference. Conclusions Conclusions The clinical efficacy of Qufeng Xuanfei and Yangyin Runzao methods for the treatment of chronic cough is safety, and its treatment effect is obvious.