摘要
In adult tissues,stem cells are defined by their unique capacity to self-renew and produce nonequivalent daughters that can differentiate into cell lineages to maintain tissue homeostasis.Misregulation of stem cell functions has been implicated in a variety of human diseases such as degenerative diseases and cancer.Thus,understanding the regulatory
In adult tissues, stem cells are defined by their unique capacity to self-renew and produce non- equivalent daughters that can differentiate into cell lineages to maintain tissue homeostasis. Misregulation of stem cell functions has been implicated in a variety of human diseases such as degenerative diseases and cancer. Thus, understanding the regulatory mechanisms of adult stem cells is important for stem cell biology and their future use in regenerative medicine.
基金
supported by the National Basic Research Program of China
the Natural Science Foundation of China
the Strategic Priority Research Program of the Chinese Academy of Sciences
