低蛋白饮食联合α-酮酸治疗慢性肾功能衰竭60例疗效观察

Clinical Efficacy of Low Protein Diet Combined with α-Ketoacid for Treating Chronic Renal Failure in 60 Cases

目的探讨低蛋白饮食联合α-酮酸治疗慢性肾功能衰竭的疗效。方法选择医院2013年6月至2016年12月收治的慢性肾功能衰竭患者120例,按随机数字表法分为两组,各60例。对照组患者予以低蛋白饮食,在此基础上,观察组患者口服α-酮酸。结果观察组总有效率为93.33%,高于对照组的80.00%(P<0.05);治疗后,观察组尿素氮、血钙水平明显优于对照组(P<0.05)。结论低蛋白饮食联合α-酮酸治疗慢性肾功能衰竭,不仅能改善钙磷代谢异常、保护残余肾功能,还能提高临床疗效。

Objective To investigate the efficacy of low protein diet combined with α-ketoacid in the treatment of chronic renal failure.Methods Totally 120 patients with chronic renal failure in our hospital from June 2013 to December 2016 were randomly divided into two groups,60 cases in each group.The control group was given low protein diet,on this basis,the observation group was treated with α-ketoacid.Results The total effective rate of the observation group was 93.33% which was higher than 80.00% of the control group（P 〈 0.05）.After treatment,the levels of BUN and Ca in the observation group were significantly better than the control group（P 〈 0.05）.Conclusion Low protein diet combined with α-ketoacid in treating chronic renal failure not only can improve renal function,protect the residual calcium and phosphate metabolism,but also conducive to improve the clinical curative effect.