海洛因依赖与人格障碍的共病研究

Comorbidity of Heroin Dependence and Personality Disorders

目的:评估海洛因依赖者中人格障碍的发生率,探讨海洛因依赖者的人格障碍共病情况。方法:采用美国精神障碍诊断与统计手册第4版人格障碍临床定式访谈量表(SCID-II)对120例海洛因依赖者和120名健康对照者进行人格障碍的评估。结果:海洛因依赖患者中人格障碍的共病率是79.2%,且73.3%的患者同时符合两种或以上的人格障碍。患者中最常见的人格障碍是边缘型、反社会型、偏执型、强迫型,男性海洛因依赖者中反社会型人格障碍的发生率显著高于女性(χ~2=11.98,P<0.01)。结论:海洛因依赖者中人格障碍的共病现象非常普遍。

Objective：To evaluate the prevalence rate of personality disorders in heroin dependence patients,and explore the comorbidity of heroin dependence and personality disorders.Methods：The SCID-II was used to assess the personality disorders in 120 heroin dependence patients and 120 matched normal controls.Results：The comorbidity rate of personality disorder in the heroin dependence patients was 79.2%,in which 73.3% were fulfilled at least two personality disorders.Boardline、antisocial、paranoid and compulsive personality disorder were most common.The prevalence rate of antisocial personality disorder in male heroin dependence patients was signficantly higher than that in female heroin dependence（χ~2=11.98,P〈0.01）.Conclusion：The comorbidity of personality disorders is much common in heroin dependence patients.