参七胶囊治疗早期糖尿病视网膜病变的临床疗效

The Clinical Effect of Shenqi Capsule in the Treatment of Early Diabetic Retinopathy

目的观察参七胶囊治疗早期糖尿病视网膜病变的临床疗效。方法选择2015年10月至2016年7月82例在本院诊断为早期糖尿病视网膜病变的患者,随机均分为两组。对照组采用西医常规治疗,观察组在此基础上加用参七胶囊治疗。观察两组治疗效果及治疗前后视力、眼底血管造影检查情况及血液流变学状况。结果两组患者经治疗后临床总有效率无统计学差异(P>0.05),观察组总有效率90.48%略高于对照组78.57%。两组经治疗后视力及眼底血管造影检查情况均明显改善(P<0.05),观察组治疗后视力明显高于对照组,微血管瘤数及出血灶面积均明显低于对照组(P<0.05)。两组治疗后血液流变学指标均明显改善,而观察组全血粘度、血浆纤维蛋白原及红细胞压积与对照组比较差异具有统计学意义(P<0.05)。结论参七胶囊治疗糖尿病视网膜病变疗效确切,患者的视力得到显著提高,其微血管瘤数、出血灶面积明显减少,血液流变学指标也得到了明显改善。

Objective To observe the clinical effect of Shenqi capsule in the treatment of early diabetic retinopathy. Methods82 patients with early diabetic retinopathy treated in our hospital from October 2015 to July 2016 were selected, and they were random-ly divided into two groups. The control group was treated with conventional western therapy, while the observation group was treatedwith Shenqi capsule on this basis. The therapeutic effects of the two groups were observed before and after treatment, as well as theirvisual acuity, fundus angiography and blood rheology. Result There was no significant difference in clinical efficacy between the twogroups （P〉0. 05）, and the total effective rate of the observation group （90. 48% ） was slightly higher than that of the control group（78.57%）. The visual acuity and fundus angiography of the two groups were significantly improved after treatment （P〈0.05） , thevisual acuity of the observation group was significantly higher than that of the control group and the number of hemangioma, togetherwith the area of hemorrhage was significantly lower than those of the control group （ P〈0. 05 ）. The hemorheology indexes of the twogroups were significantly improved after treatment, and the whole blood viscosity, plasma fibrinogen and hematocrit of the observationgroup were significantly different from those of the control group （ P〈0. 05 ）. Conclusion Shenqi capsule has an obvious therapeuticeffect on diabetic retinopathy which is embodied in such a way that visual acuity of the patients was significantly improved, the numberof microvessels and the area of hemorrhage were decreased obviously, and the indexes of hemorheology were improved remarkably.