常见神经心理疾病的认知电位特征

The characteristics of higher cogni tive potential of brain in clinical assessment

任何一个心理活动都伴有大脑神经电生理的变化,多种事件相关脑诱发电位,如P300、N400、MMN等被认为是大脑皮层活动的整合结果,与大脑复杂的认知过程有关,又称之为认知电位,可作为判断大脑高级功能的一个客观指标,用于神经精神科临床和心理学研究。因此,探讨和研究常见神经心理疾病的认知电位特征并应用到疾病的早期诊断、治疗、预后等临床工作中将具有极其重要的意义。

Psychomotilities were co mm only associated with changes of neural electrophysiology in brain,and many even t-related potentials(ERPs )of brain,such as P300,N400,MMN,et a l, were considered as integration of connection cerebral cortex activit y,correlat ed with cog-nitive process and complexity.Then event-related potentials were called as cognitive potentials which were considered the objective criteria of h igher functions of brain and applie d in clinical of neuropsychiatry and psychol ogical research.Therefore,it was significance that investigation of the charac teristics for higher cognitive potential in usually neurop sychiatric disease an d used in clini cal,include early diagnosis,treatment,rehabilitation,and pre diction.