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地塞米松联合托烷司琼对腹腔镜胃大部切除术肥胖患者术后恶心呕吐的影响 被引量:3

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摘要 目的评价地塞米松联合托烷司琼对腹腔镜下胃大部切除患者术后恶心呕吐(postoperative nausea and vomiting,PONV)的影响。方法择期全麻腹腔镜下胃大部切除术的肥胖患者100例,采用随机数字表法分为2组各50例,对照组(C组)和地塞米松联合托烷司琼组(DT组)。DT组患者于气管插管后即刻静脉注射地塞米松4 mg、缝皮时静脉注射托烷司琼5 mg,C组患者于相同时间点给予等量的生理盐水。比较两组患者PONV发生情况。计量资料比较采用t检验,计数资料比较采用χ~2检验,P<0.05为差异有统计学意义。结果与C组比较,DT组患者术后24 h内总恶心发生率(58.0%、24.0%)、总呕吐发生率(26.0%、6.0%)及止吐补救措施所占的比例(66.0%、20.0%)均明显降低,差异均有统计学意义(均P<0.05)。结论地塞米松联合托烷司琼可降低腹腔镜下胃大部切除患者PONV的发生率。
作者 苗亚飞
出处 《社区医学杂志》 2017年第13期60-62,75,共4页 Journal Of Community Medicine
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