HPV感染对产后出血与围产儿结局的对照研究

The Postpartum Hemorrhage and Perinatal Outcomes Impact of the Pregnancy Complicated with Infection of Human Papillomavirus(HPV)

目的:探讨妇女妊娠期生殖道HPV感染对产后出血、围产儿结局的影响情况。方法:选取2013年11月~2016年2月在本社区初次建卡孕期筛查生殖道HPV感染孕妇100例作为观察组,同期选取初次建卡正常孕妇120例作为对照组。跟踪观察两组研究对象产后出血、围产儿结局情况。结果:观察组早产、胎儿窘迫、新生儿窒息、新生儿HPV感染发生率均高于对照组,差异均有统计学意义(P<0.05);两组产后出血比较差异无统计学意义(P>0.05)。结论:妇女妊娠期生殖道HPV感染对围产儿结局会造成不良影响,准备受孕的妇女应进行积极有效的治疗。HPV感染是否导致更高的产后出血则有待进一步观察。

Objective： To analyze the postpartum hemorrhage and perinatal outcomes impact of the pregnancy complicated with infection of human papillomavirus（HPV）. Methods： 100 pregnant women infected with HPV were selected as the observation group in our community from Nov 2013 to Feb 2016,while another 120 normal pregnant women were selected as the control group. The postpartum hemorrhage and perinatal outcomes of the two groups were observed. Results： The difference of postpartum hemorrhage in the two groups had no statistical significance（P〉0. 05）. The incidence rate of premature delivery,fetal distress,asphyxia neonatorum and the neonatus with HPV infection of the observation group were higher than that of control group. The differences had statistical significance（P〈0. 05）. Conclusion： The pregnancy complicated with infection of human papillomavirus（HPV） can cause adverse impact on the postpartum hemorrhage and perinatal outcomes,the women who are ready to get pregnant should recieve effective treatment.