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2014-2016年某院腹腔感染病原菌分布及耐药性分析 被引量:8

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摘要 目的分析腹腔感染病原菌分布及耐药性,以期为临床合理用药提供依据。方法收集某院2014-2016年分离自门诊及住院患者腹腔标本的病原菌资料,应用Whonet 5.6软件进行统计分析。结果 3年共检出病原菌421株,其中革兰阴性杆菌249株(59.14%),革兰阳性菌155株(36.82%),真菌17株(4.04%);大肠埃希菌和肺炎克雷伯菌产超广谱β-内酰胺酶(ESBLs)的检出率分别为62.50%、36.70%,耐碳青酶烯类抗菌药物的肠杆菌科细菌(CRE)的发生率大肠埃希菌为5.80%,肺炎克雷伯菌为17.40%,鲍曼不动杆菌除了对米诺环素敏感性为44.40%外,对其它常用抗菌药物的敏感性均小于20.00%;屎肠球菌和粪肠球菌对万古霉素和替考拉宁均保持100.00%的抗菌活性;金黄色葡萄球菌和表皮葡萄球菌对万古霉素、替考拉宁、利奈唑胺均保持100.00%抗菌活性,耐甲氧西林金黄色葡萄球菌(MRSA)和耐甲氧西林表皮葡萄球菌(MRSE)的发生率分别为36.40%,81.00%。结论腹腔感染病原菌主要以肠杆菌和肠球菌为主,也有真菌感染发生,肠杆菌科细菌耐药率较高,泛耐药鲍曼不动杆菌很高,耐药形势严峻,临床要尽早规范留取标本,尽早确定致病菌,尽早合理使用抗菌药物治疗。
机构地区 焦作市人民医院
出处 《河南预防医学杂志》 2017年第9期674-676,F0003,共4页 Henan Journal of Preventive Medicine
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