不同腹腔压对呼吸衰竭患者神经调节辅助通气EADi和呼吸功能的影响

Effects of different intraperitoneal pressure on neurally adjusted assisted ventilation EADi and respiratory function in the patients with respiratory failure

目的分析不同腹腔压在呼吸衰竭及其对神经调节辅助通气膈肌电活动(EADi)和呼吸功能的影响。方法选取2015年1月~2016年1月50例医院收治呼吸衰竭患者作为观察对象,所有患者均采用神经调节辅助通气,根据国际腹间隙综合征学会对高腹腔压(腹腔压≥12 mm Hg)的定义将患者分为高腹压组和非高腹压组。观察两组患者的每小时EADi值与潮气量。结果高腹压组EADi值方面均显著低于非高腹压组(P<0.05),而在潮气量方面则显著高于非高腹压组(P<0.05)。结论在应用神经调节辅助通气时,高腹腔压会使得EADi值下降而潮气量升高;非高腹压时则会使得EADi值升高而潮气量下降。

Objective To investigate the effects of different abdominal pressure on respiratory failure and its effect on the neurally adjusted assisted ventilation diaphragm electrical activity（EADi） and respiratory function. Methods 50 patients with respiratory failure who were admitted to our hospital from January 2015 to January 2016 were selected as the ob- servation subjects. All patients were given neurally adjusted assisted ventilation. According to the definition of high ab- dominal pressure （intraperitoneal pressure〉 12 mmHg）by the International Abdominal Compartment Syndrome Associa- tion, the patients were divided into high abdominal pressure group and non-high abdominal pressure group. The EADi values and tidal volume per hour were observed in both groups. Results The EADi values in the high abdominal pres- sure group were significantly lower than those in the non-high abdominal pressure group（P〈0.05）, but the tidal volume was significantly higher than that in the non-high abdominal pressure group（P〈0.05）. Conclusion In the application of neurally adjusted assisted ventilation, high abdominal pressure makes the EADi value decreased and tidal volume in- creased; non-high abdominal pressure makes the EADi value increased and tidal volume decreased.