2011年–2014年成都市21家医院铂类抗肿瘤药物使用情况分析

Analysis on utilization of antitumor platinum drugs in 21 hospitals of Chengdu from 2011 to 2014

目的评价2011年—2014年成都市21家医院铂类药物的使用情况。方法调取成都市21家医院2011年—2014年铂类药物的相关用药信息,统计分析药物剂型、使用金额、用药频度(frequency of drug use,DDDs)、日均费用(defined daily cost,DDC)及药品排序比[药品使用金额排序(B)与各药DDDs排序(A)的比值,B/A]。结果 2011年—2014年铂类药物的总使用金额和DDDs逐年增长,奥沙利铂使用金额最高,卡铂的使用金额逐年递增。从排序来看,奥沙利铂、奈达铂、洛铂连续4年排名均为第1、2、5位;2011年—2014年铂类药物总DDDs呈上升趋势,顺铂的DDDs排名持续居于首位,奥沙利铂其次;铂类药物的DDC及排序相对稳定,卡铂和洛铂的B/A值接近于1.00。结论成都市医院铂类药物使用符合安全有效、方便经济的原则。

Objective To investigate the utilization of platinum drugs in 21 hospitals of Chengdu from 2011 to 2014. Methods The utilization information of platinum drugs in 21 hospitals of Chengdu from 2011 to 2014 was extracted, and the dosage form of drugs, consumption sum, frequency of drug use （DDDs）, defined daily cost （DDC）, and drug sequence ratio （B/A） were analyzed statistically. Results From 2011 to 2014, the total consumption sums and DDDs of platinum drugs were increased year by year. The consumption sums of oxaliplatin were the highest, and the consumption sums of carboplatin were increased year by year. Oxaliplatin, nedaplatin, and lobaplatin were ranked first, second and fifth respectively in all the four consecutive years; the total DDDs ofpatinum drugs from 2011 to 2014 showed a trend of increase, DDDs of cisplatin were always ranked first, followed by oxaliplatin; DDC and sorting of platinum drugs were relatively stable, and B/A values of carboplatin and cisplatin were close to 1.00. Conclusion The utilization of platinum drugs in 21 hospitals of Chengdu is in accordance with the principle of safety, effectiveness, economy and convenience.