中药足浴联合湿润烧伤膏治疗1～2级糖尿病足临床体会

Clinical Experience in the Treatment of Wagner Grade 1 & 2 Diabetic Foot Ulcers by Chinese Medicine Foot Bath in Combination with MEBO

目的探讨中药足浴联合湿润烧伤膏治疗1~2级糖尿病足的临床疗效。方法将2015年7月—2016年12月大连医科大学附属第二医院创面修复科收治的90例1~2级糖尿病足患者随机分为观察组(45例)与对照组(45例),观察组患者在中药足浴后外敷湿润烧伤膏治疗溃疡创面,对照组患者在中药足浴后外敷凡士林纱布治疗溃疡创面,对比观察两组患者创面愈合时间及愈合效果。结果观察组患者创面愈合时间为(14.24±3.17)d,对照组患者创面愈合时间为(21.56±4.82)d;治疗2周后,观察组患者痊愈12例,显效18例,好转14例,无效1例,总有效率为97.78%,对照组患者痊愈7例,显效17例,好转9例,无效12例,总有效率为73.33%。两组患者创面愈合时间及愈合效果对比,P均<0.05,差异具有统计学意义。结论中药足浴联合湿润烧伤膏治疗1~2级糖尿病足,可有效缩短创面愈合时间,提高创面愈合效果,疗效显著,值得临床推广应用。

Objective To explore the clinical efficacy of Chinese Medicine foot bath in combination with Moist Exposed Burn Ointment （MEBO） in the treatment of Wagner grade 1 or 2 diabetic foot ulcers. Methods Ninety patients with diabetic foot ulcer （ Wagner grade 1 or 2 ） admitted to Wound Repair Department of The Second Hospital of Dalian Medical University between July 2015 and December 2016 were randomly distributed into a treatment group （45 patients） and a control group （45 patients）. Patients in the treatment group were treated by the Chinese Medicine foot bath followed by the external application of MEBO while patients in the control group were treated by the Chinese Medicine foot bath followed by the external application of Vaseline gauze. The wound healing time and clinical outcomes were observed and compared between the two groups. Results The wound healing time in the treatment group was （ 14. 24 ±3. 17 ） d while that in the control group was （21.56 ±4. 82） d; after two weeks of treatment, in the treatment group 12 patients were cured, and the therapy was markedly effective in 18 patients, effective in 14 patients and ineffective in 1 patient with a total effec- tive rate of 97.78%, while in the control group 7 patients were cured, and the treatment was markedly effective in 17 patients, effective in 9 patients and ineffective in 12 patients with a total effective rate of 73.33%. The comparison between the two groups in terms of wound healing time and healing effect showed statistically significant differences （both P 〈 0. 05 ）. Conclusion Treating diabetic foot ulcers （ Wagner grade 1 and 2） with the Chinese Medicine foot bath in combination with MEBO can effectively reduce the wound healing time and improve the patients＇ outcomes, which can be promo- ted in clinical practice.