有晶体眼后房型人工晶体植入与飞秒激光微小切口角膜基质透镜切除术矫正高度近视对眼表影响分析

Analysis of the effects of implantable contact lens and femtosecond laser small incision lenticule extraction for high myopia on ocular surface

目的比较有晶体眼后房型人工晶体(ICL)植入与全飞秒激光微小切口角膜基质透镜切除术(SMILE)对高度近视患者眼表的影响。方法高度近视患者23例(46眼)分为两组,11例(22眼)行SMILE,12例(24眼)行ICL植入术,比较两组患者术后1个月、3个月的泪膜破裂时间及泪河高度。结果术后1个月,两组患者平均泪膜破裂时间均短于术前,两组患者泪河高度均低于术前,差异均无统计学意义。术后3个月,两组患者平均泪膜破裂时间基本恢复至术前水平,两组患者泪河高度低于术前,差异均无统计学意义。结论 ICL植入与SMILE对患者泪膜破裂时间及泪河高度的影响无明显差异,手术后的泪河高度降低可能与术后用药有关。

Objective To compare differences in tear rupture time and tear meniscus height between patients with high myopia who received an implantable contact lens （ICL） or who underwent femtosecond laser small incision lenticule ex- traction（SMILE）. Methods Of 23 patients （46 eyes） with high myopia, 11 （22 eyes） underwent SMILE and 12 （24 eyes） underwent ICL. At 1 and 3 postoperative months, the two groups were compared for tear film rupture time and tear stream height differences, and statistical analysis of the results was performed. Results The mean tear-film rupture times in the ICL group and SMILE group were shorter than before surgery, but there was no significant difference be- tween the two groups （ P 〉 0.05 ）. The mean tear-film rupture time returned to preoperative levels at 3 months after sur- gery. The tear meniscus height in the ICL group and the SMILE group was still lower than before surgery, but the difference was not statistically significant （ P 〉 0.05 ）. Conclusion There was no significant difference in tear-film rupture time and tear meniscus height between posterior chamber ICL and SMILE. The reduced tear meniscus height af- ter surgery may be related to medication.