丙种球蛋白治疗小儿川崎病应用效果观察

Observation on the Effect of Gamma Globulin in Children With Kawasaki Disease

目的观察在小儿川崎病的治疗中应用丙种球蛋白的治疗效果。方法将川崎病患儿102例随机分为对照组51例和观察组51例,两组分别应用丙种球蛋白常规剂量和大剂量治疗,比较两组的治疗结果。结果观察组的治疗有效率高于对照组,临床症状消失时间短于对照组,P<0.05,两组的不良反应发生率比较差异无统计学意义,P>0.05。结论在小儿川崎病的治疗中应用大剂量的丙种球蛋白可加快患儿的康复,提高治疗效果。

Objective To observe the therapeutic effect of gamma globulin in the treatment of children with Kawasaki disease. Methods 102 children with Kawasaki disease were randomly divided into control group （51 cases） and observation group （51 cases）. The two groups were treated with routine and high dose of gamma globulin. The treatment results were compared between the two groups. Results The effective rate of treatment was higher than that of the control group. The disappearance time of clinical symptoms was shorter than that of the control group （P 〈 0.05）. There was no significant difference in the incidence of adverse reactions between the two groups （P 〉 0.05）. Conclusion The application of high dose of gamma globulin in children with Kawasaki disease can speed up the rehabilitation of children and improve the therapeutic effect.