单纯放疗、新辅助化疗及同步放化疗治疗宫颈癌临床近期疗效比较

Clinical Efficacy of Radiotherapy Alone,Neoadjuvant Chemotherapy and Concurrent Chemoradiotherapy in the Treatment of Cervical Cancer

目的对比单纯放疗、新辅助化疗、同步放化疗这几种不同方法治疗宫颈癌的临床效果。方法将100例宫颈癌患者纳入研究,其中有60例患者接受手术治疗,在手术之前为患者开展放化疗治疗,平均将患者分为A、B、C三组,分别接受单纯放疗、新辅助化疗、同步放化疗治疗;40例患者采取非手术方法进行治疗,平均分为甲、乙两组,分别接受单纯放疗和同步放化疗治疗。对比不同治疗方法的效果。结果在术前治疗患者中,A组患者近期治疗有效率低于B、C两组(P<0.05),淋巴结节转移率高于B、C两组(P<0.05);在非手术治疗患者中,甲组患者肿瘤缩小的程度小于对乙组(P<0.05)。结论对于手术患者而言,采取同步放化疗和新辅助化疗的治疗效果好于单纯放疗。对于非手术患者而言,同步放化疗治疗效果好于单纯放疗治疗。

Objective To compare the curative effect of radiotherapy, neoadjuvant chemotherapy and concurrent chemoradiotherapy on cervical cancer. Methods 100 patients with cervical cancer were included in the study. Among them, 60 patients underwent surgical treatment. Patients were divided into A, B and C group by radiotherapy and chemotherapy before operation. The patients were treated with radiotherapy alone and neoadjuvant Chemotherapy, concurrent radiotherapy and chemotherapy. 40 patients were treated by non-surgical methods, were divided into group A and group B were treated with radiotherapy alone and concurrent radiotherapy and chemotherapy. The effects of different treatments Compared. Results In the preoperative treatment, the effective rate of treatment in group A was significantly lower than that in group B and group C （P 〈 0.05）. The lymph node metastasis rate was significantly higher than that of group B and group C （P 〈 0.05）. The degree of tumor shrinkage in group A was significantly lower than that in group B （P 〈 0.05）. Conclusion For surgical patients, the effect of concurrent chemoradiotherapy and neoadjuvant chemotherapy is better than radiotherapy alone. For non surgical patients, the effect of concurrent chemoradiotherapy is better than radiotherapy alone.