血清降钙素水平检测在肺部感染用药指导及疗效评价中的应用分析

Application of PCT Levels in the Efficacy Evaluation and Medication Guidance for Pulmonary Infection

目的探讨血清降钙素水平检测在肺部感染用药指导和疗效评价中的应用价值。方法按照数字表随机分组法,将我院收治的73例肺部感染患者分为两组。对照组依据临床医生经验使用抗菌药物,而观察组则根据血清PCT水平指导抗菌药应用。比较两组抗菌药物使用情况及临床疗效,比较不同疗效患者之间的血清PCT水平。结果观察组抗生素使用时间、使用比例及临床总有效率均优于对照组,组间对比,差异有统计学意义(P<0.05)。痊愈患者的血清PCT水平低于其他疗效患者(P<0.05)。结论血清PCT水平可有效指导肺部感染患者的临床用药,可作为临床疗效的直观评价指标。

Objective To explore the application of PCT levels in the efficacy evaluation and medication guidance for pulmonary infection.Methods According to the digital table random grouping method, 73 cases of pulmonary infection were divided into two groups. The control group was treated with antibiotics according to the clinician＇s experience, the observation group based on serum PCT level to guide the application of antibiotics. The use of antibacterials and clinical efficacy were compared between the two groups, serum PCT levels were compared among patients with different efficacy. Results The observation group was significantly better than the control group in the antimicrobial use time, antimicrobial use ratio and total effective rate, the difference was statistically significant （P〈0.05）. The cured patients were significantly lower than other patients in serum calcitonin levels, the difference was statistically significant （P〈0.05）. Conclusion Serum PCT levels can be used as visual indicators in the efficacy evaluation and medication guidance for pulmonary infection.