探讨更昔洛韦治疗疱疹性咽峡炎的临床疗效和药理作用

To Investigate the Clinical Efficacy and Pharmacological Effect of Ganciclovir in the Treatment of Herpangina

目的对疱疹性咽峡炎患者使用更昔洛韦治疗的临床效果进行研究,对其药理作用进行分析。方法选取2012年1月—2013年1月某院收治的90例疱疹性咽峡炎患者作为研究对象。将患儿分为对照组和治疗组,每组均有45例。对照组采用肠管治疗,治疗组采用更昔洛韦治疗,对两组患者的临床治疗效果进行对比分析。结果经过治疗,治疗组的临床治疗有效率为95.56%,对照组为75.56%,两组结果对比,差异具有统计学意义(P<0.05)。治疗组体温回复正常时间平均为(2.35±0.23)d,疱疹平均消失时间为(4.56±1.34)d,平均住院天数为(6.32±1.02)d;对照组分别为(4.33±0.82)d、(6.34±0.97)d、(8.33±2.57)d;两组指标对比,差异具有统计学意义(P<0.05)。结论疱疹性咽峡炎患者接受更昔洛韦治疗的效果显著,患者的病情恢复良好。

Objective To study the clinical effect of patients with herpangina ganciclovir, its pharmacological effects are analyzed. Methods 90 cases of herpangina were selected from January 2012 to January 2013 in a hospital as the research object, the children were divided into control group and treatment group, 45 cases in each group. The control group was treated with intestinal tract, and the treatment group was treated with ganciclovir. The clinical effects of the two groups Were compared and analyzed. Results After treatment, the effective rate of the clinical treatment group was 95.56%, the control group was 75.56%, and the difference between the two groups was statistically significant （P 〈 0.05）. The average time of normal temperature recovery in the treatment group was （2.35 ± 0.23） d, the average disappearance time of herpes was （4.56 ± 1.34） d, and the average length of stay was （6.32 ± 1.02） d. The control group was （4.33 ± 0.82） d, （6.34 ± 0.97） d, （8.33 ± 2.57） d, the difference between the two groups was statistically significant （P 〈 0.05）. Conclusion Herpetic angina patients received ganciclovir treatment effect, the patient recovered well .